Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28332620 | 1.00 | LMNA (0.38) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL27326152 | 0.86 | LMNA (0.38) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL7856018 | 0.84 | LMNA (0.39) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL10395459 | 0.81 | LMNA (0.41) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL27869201 | 0.81 | LMNA (0.41) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL686672 | 0.81 | LMNA (0.41) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL7096584 | 0.81 | LMNA (0.41) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL9247356 | 0.81 | LMNA (0.34) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL10394692 | 0.79 | MAPT (0.33) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL11154542 | 0.79 | LMNA (0.39) | LMNAMAPTDNM1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507269-B1 | THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | GRACE W R & CO (US) | 2014-10-29 | — | — | EP | disclosed |
| EP-2507268-B1 | TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | GRACE W R & CO (US) | 2014-10-15 | — | — | EP | disclosed |
| US-8633126-B2 | Three and four atom bridged dicarbonate compounds as internal donors in catalysts for polypropylene manufacture | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-01-21 | — | — | US | disclosed |
| US-20130245306-A1 | TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-09-19 | — | — | US | disclosed |
| EP-2507268-A1 | TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | Dow Global Technologies LLC (US) | 2012-10-10 | — | — | EP | disclosed |
| EP-2507269-A1 | THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | Dow Global Technologies LLC (US) | 2012-10-10 | — | — | EP | disclosed |
| US-8263520-B2 | Two atom bridged dicarbonate compounds as internal donors in catalysts for polypropylene manufacture | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-09-11 | — | — | US | disclosed |
| WO-2011068775-A1 | THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011068770-A1 | TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-06-09 | — | — | WO | disclosed |
| US-20110130530-A1 | TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-06-02 | — | — | US | disclosed |
| EP-0216402-A2 | Preparation of spherical magnesium alkoxide particles | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-04-01 | — | — | EP | disclosed |
| US-4548915-A | ABSORPTION OF MINERAL OIL INTO CATALYST PORES-STORAGE STABILITY | SHELL OIL COMPANY (US) | 1985-10-22 | — | — | US | disclosed |
| US-4535068-A | HALOGENATING 4 MAGNESIUM COMPOUND WITH TITANIUM HALIDE;CONTACTING WITH ACID HALIDE | SHELL OIL COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0135973-A2 | Olefin polymerization catalyst components and polymerization process | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1985-04-03 | — | — | EP | disclosed |
| US-4497905-A | HALOGENATED MAGNESIUM ALKOXIDE COMPOUND, TITANIUM, ALUMINUM AND THIONYL CHLORIDE COMPONENTS | SHELL OIL COMPANY (US) | 1985-02-05 | — | — | US | disclosed |
| US-4414132-A | Olefin polymerization catalyst compositions and a process for the polymerization of olefins employing such compositions | SHELL OIL COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0019312-B1 | OLEFIN POLYMERIZATION CATALYST COMPOSITIONS AND A PROCESS FOR THE POLYMERIZATION OF OLEFINS EMPLOYING SUCH COMPOSITIONS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-08-17 | — | — | EP | disclosed |
| US-4393182-A | ORGANOALUMINUM COMPOUND, ELECTRON DONOR | SHELL OIL COMPANY (US) | 1983-07-12 | — | — | US | disclosed |
| US-4329253-A | MAGNESIUM HALIDE, TITANIUM HALIDE, ORGANIC ELECTRON DONOR REACTION PRODUCT | SHELL OIL COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0019312-A1 | Olefin polymerization catalyst compositions and a process for the polymerization of olefins employing such compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130530-A1 | TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | XRN2, TERF2, RAD52 | LMNA 2712/4885MAPT 1481/4885DNM1 2021/4885 |
| US-20130245306-A1 | TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | HPD, TERT, DDT | LMNA 3332/4885MAPT 2217/4885DNM1 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.