SCHEMBL686672

SCHEMBL686672

CCCCCCC(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
DNM1 Q05193 2/20 0.40
TSHR P16473 2/20 0.40
THRB P10828 1/20 0.40
OPRM1 P35372 1/20 0.39
ALDH1A1 P00352 1/20 0.38
FDPS P14324 4/20 0.37
GPR84 Q9NQS5 3/20 0.37
SPHK1 Q9NYA1 1/20 0.37
FFAR1 O14842 1/20 0.37
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10395459 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL27869201 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL7096584 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL8891317 0.97 OPRM1 (0.40) LMNADNM1TSHRTHRBOPRM1
SCHEMBL11314071 0.91 OPRM1 (0.38) LMNADNM1TSHRTHRBOPRM1
SCHEMBL8465036 0.90 DNM1 (0.38) LMNADNM1TSHRTHRBOPRM1
SCHEMBL16970044 0.86 LMNA (0.43) LMNADNM1FDPSGPR84SPHK1
SCHEMBL16969588 0.86 LMNA (0.43) LMNADNM1FDPSGPR84SPHK1
SCHEMBL577931 0.86 LMNA (0.43) LMNADNM1FDPSGPR84SPHK1
SCHEMBL16970042 0.86 LMNA (0.43) LMNADNM1FDPSGPR84SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843939-B Polyolefin with low ash content and method for preparing same 格雷斯公司 2024-04-26 CN disclosed
EP-3074429-B1 PRODUCING PROPYLENE IMPACT COPOLYMERS AND PRODUCTS GRACE W R & CO (US) 2024-01-24 EP disclosed
EP-3837290-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2023-05-10 EP disclosed
US-11591458-B2 Polyolefins with low ash content and method of making same W.R. GRACE & CO.-CONN. (US) 2023-02-28 US disclosed
CN-115160459-A Catalyst systems for producing polyolefins and methods of making and using the same 格雷斯公司 2022-10-11 CN disclosed
CN-110023351-B Main catalyst composition prepared by combining internal electron donors 格雷斯公司 2022-04-26 CN disclosed
US-11236222-B2 Catalyst system for the production of polyolefins and method of making and using same W.R. GRACE & CO.-CONN. (US) 2022-02-01 US disclosed
US-11220519-B2 Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-01-11 US disclosed
CN-112437780-B Components and catalysts for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2021-11-05 CN disclosed
US-20210309676-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2021-10-07 US disclosed
US-5077357-A Titanium procatalyst and organoaluminum cocatalyst SHELL OIL COMPANY (US) 1991-12-31 US disclosed
US-5066737-A Complex Titanium-Magnesium Procatalyst, Organoaluminum Cocatalyst And A Selectivity Control Agent SHELL OIL COMPANY (US) 1991-11-19 US disclosed
CN-1044833-A Dimensionally stable polyester yarn for processing highly dimensionally stable yarn ALLIED SIGNAL INC (US) 1990-08-22 CN disclosed
CN-1039854-A The high-intensity treated line of the polyester yarn of dimensionally stable-be used for ALLIED SIGNAL INC (US) 1990-02-21 CN disclosed
CN-1033255-A The metallic plate of lamination METAL BOX PLC (GB) 1989-06-07 CN disclosed
CN-1033256-A The metallic plate of lamination METAL BOX PLC (GB) 1989-06-07 CN disclosed
CN-1032765-A LAMINATED METAL SHEET MB GROUP PLC (GB) 1989-05-10 CN disclosed
CN-1032764-A The laminate of polyolefine thin film and metal and production method thereof MB GROUP PLC (GB) 1989-05-10 CN disclosed
CN-1032767-A The metal can ends of band vinyl cover MB GROUP PLC (GB) 1989-05-10 CN disclosed
US-4818575-A Biaxially drawn polyester vessel having resistance to heat distortion and gas barrier properties and process for preparation thereof TOYO SEIKAN KAISHA, LTD. (JP) 1989-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210309676-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS COG4, SCO2, COG2 LMNA 3835/4885DNM1 1820/4885TSHR 2535/4885
US-11220519-B2 Components and catalysts for the polymerization of olefins COG4, SCO2, COG2 LMNA 3835/4885DNM1 1820/4885TSHR 2535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.