Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | GCLC | P48506 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247581 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KMT2AMETAP2GCLCMMP1 | |
| SCHEMBL9243534 | 0.95 | GCLC (0.41) | ALDH1A1KMT2AMETAP2GCLCMMP1 | |
| SCHEMBL9244187 | 0.83 | MMP1 (0.41) | ALDH1A1KMT2AGCLCMMP1MMP13 | |
| SCHEMBL9244602 | 0.79 | LTA4H (0.43) | MMP1MMP13LTA4H | |
| SCHEMBL5372466 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KMT2AMETAP2LTA4H | |
| SCHEMBL8735264 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KMT2AMETAP2LTA4H | |
| SCHEMBL8737248 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KMT2AMETAP2LTA4H | |
| SCHEMBL8737263 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KMT2AMETAP2LTA4H | |
| SCHEMBL28807909 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KMT2AMETAP2LTA4H | |
| SCHEMBL9647093 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KMT2AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347840-B1 | Phosphinic acid derivates | BANYU PHARMA CO LTD (JP) | 1995-12-27 | — | — | EP | disclosed |
| US-4988681-A | Dipeptidase inhibitore; reducing renal toxicity; prevention deactivation of (carba)penem antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0347840-A2 | Phosphinic acid derivates | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |