Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247329 | 0.89 | KCNH2 (0.51) | KCNH2LMNAGABRPGABRDGABRA1 | |
| SCHEMBL9248307 | 0.87 | KCNH2 (0.54) | KCNH2LMNATNK2MMP2MMP9 | |
| SCHEMBL9249053 | 0.84 | KCNH2 (0.49) | KCNH2LMNAGABRPGABRDGABRA1 | |
| SCHEMBL5886646 | 0.82 | KCNH2 (0.55) | KCNH2LMNAGABRPGABRDGABRA1 | |
| SCHEMBL20152451 | 0.81 | TSHR (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9246426 | 0.81 | GABRP (0.41) | KCNH2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11549533 | 0.81 | LMNA (0.40) | KCNH2LMNAGABRPGABRDGABRA1 | |
| SCHEMBL9249056 | 0.81 | MCHR1 (0.48) | KCNH2KDM4EMAPT | |
| SCHEMBL9248158 | 0.80 | RAB9A (0.49) | KCNH2KDM4EMAPT | |
| SCHEMBL5886641 | 0.79 | KCNH2 (0.60) | KCNH2LMNATNK2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447657-A | Liquid crystal compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |