Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097678 | 0.81 | ERN1 (0.40) | ALDH1A1 | |
| SCHEMBL2097245 | 0.76 | ERN1 (0.40) | ALDH1A1 | |
| SCHEMBL10877523 | 0.74 | VCAM1 (0.37) | — | |
| SCHEMBL7528985 | 0.73 | GAA (0.41) | ALDH1A1 | |
| SCHEMBL22704981 | 0.72 | GAA (0.32) | — | |
| SCHEMBL10965986 | 0.72 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL14855436 | 0.72 | KMT2A (0.43) | — | |
| SCHEMBL2094079 | 0.71 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL23981950 | 0.70 | MAPT (0.42) | ALDH1A1 | |
| SCHEMBL9666686 | 0.69 | CA12 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393913-A | N-formylanilines | RHONE-POULENC INC. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0599183-A1 | Manufacturing of pesticides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1994-06-01 | — | — | EP | disclosed |
| US-4511720-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4355033-A | TREATMENT OF HYPERTENSION | HOFFMAN-LA ROCHE INC. (US) | 1982-10-19 | — | — | US | disclosed |
| EP-0002010-B1 | DERIVATIVES OF 2-IMINO-IMIDAZOLIDINE, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-07-14 | — | — | EP | disclosed |
| US-4244957-A | HYPOTENSIVE AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1981-01-13 | — | — | US | disclosed |
| EP-0002010-A1 | Derivatives of 2-imino-imidazolidine, processes for their preparation, pharmaceutical compositions containing them and intermediates | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-05-30 | — | — | EP | disclosed |