Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13623166 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ATDP1CYP2A6 | |
| SCHEMBL7528740 | 0.85 | GAA (0.46) | ALDH1A1MEN1KMT2ATDP1GAA | |
| SCHEMBL16240433 | 0.85 | TDP1 (0.40) | ALDH1A1MEN1KMT2ATDP1GAA | |
| SCHEMBL27851425 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ATDP1GAA | |
| SCHEMBL21461560 | 0.85 | GAA (0.45) | ALDH1A1MEN1KMT2ATDP1GAA | |
| SCHEMBL11614677 | 0.80 | PTGS2 (0.46) | ALDH1A1MEN1KMT2ATDP1TYK2 | |
| SCHEMBL2097678 | 0.75 | ERN1 (0.40) | ALDH1A1MEN1KMT2ATDP1GAA | |
| SCHEMBL11915484 | 0.75 | CYP1A2 (0.38) | ALDH1A1MEN1KMT2ATDP1GAA | |
| SCHEMBL448938 | 0.75 | MEN1 (0.50) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL20341641 | 0.73 | TDP1 (0.38) | ALDH1A1MEN1KMT2ATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| US-4935515-A | ANTIARRHYTHMIA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-06-19 | — | — | US | claimed |
| EP-0358749-A1 | 1,4-SUBSTITUTED-2,3,5,6-TETRAHYDRO 1,3,6]TRIAZOCINO 1,2-a]BENZIMIDAZOLES AND INTERMEDIATES THEREFOR | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-03-21 | — | — | EP | claimed |
| WO-1989008111-A1 | 1,4-SUBSTITUTED-2,3,5,6-TETRAHYDRO[1,3,6]TRIAZOCINO[1,2-a]BENZIMIDAZOLES AND INTERMEDIATES THEREFOR | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-09-08 | — | — | WO | claimed |
| US-4801706-A | ANTIARRHYTHMIA HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-31 | — | — | US | claimed |
| JP-55072152-A | — | — | None | — | — | JP | disclosed |
| US-20260007638-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF CLONIDINE | AZURITY PHARMACEUTICALS, INC. (US) | 2026-01-08 | — | — | US | disclosed |
| US-12440474-B2 | Stable pharmaceutical compositions of clonidine | AZURITY PHARMACEUTICALS, INC. (US) | 2025-10-14 | — | — | US | disclosed |
| US-20250152558-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF CLONIDINE | SLAYBACK PHARMA LLC (US) | 2025-05-15 | — | — | US | disclosed |
| US-12233049-B2 | Stable pharmaceutical compositions of clonidine | SLAYBACK PHARMA LLC (US) | 2025-02-25 | — | — | US | disclosed |
| US-20230149359-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF CLONIDINE | AZURITY PHARMACEUTICALS, INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230149359-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF CLONIDINE | AZURITY PHARMACEUTICALS, INC. | 2023-05-18 | — | — | US | disclosed |
| EP-0002010-B1 | DERIVATIVES OF 2-IMINO-IMIDAZOLIDINE, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-07-14 | — | — | EP | disclosed |
| EP-0003259-B1 | N-FORMYLANILIDO AROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PROCESS FOR THE PREPARATION OF THE CORRESPONDING N-PHENYL AROMATIC AMINO COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-24 | — | — | EP | disclosed |
| US-4292446-A | N-FORMYLANILINO AROMATICS, DIPHENYLAMINE INTERMEDIATES, PESTICIDES, PREPARATION FROM FORMANILIDES AND HALOAROMATICS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-09-29 | — | — | US | disclosed |
| US-4244957-A | HYPOTENSIVE AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1981-01-13 | — | — | US | disclosed |
| JP-S5572152-A | PREPARATION OF 2-(2,6-DICHLOROANILINO)PHENYLACETIC ACID AND ITS SALT | TAIYO YAKUHIN KOGYO KK | 1980-05-30 | — | — | JP | disclosed |
| EP-0003259-A1 | N-Formylanilido aromatic compounds, process for their preparation and process for the preparation of the corresponding N-phenyl aromatic amino compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-08-08 | — | — | EP | disclosed |
| EP-0002010-A1 | Derivatives of 2-imino-imidazolidine, processes for their preparation, pharmaceutical compositions containing them and intermediates | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-05-30 | — | — | EP | disclosed |
| US-4024259-A | 3-Anilino-2,4-diazabicyclo[3.2.1]octenes | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12440474-B2 | Stable pharmaceutical compositions of clonidine | ADRA2C, SLC6A2, ADRA2A | ALDH1A1 1934/4885MEN1 2539/4885KMT2A 2550/4885 |
| US-12233049-B2 | Stable pharmaceutical compositions of clonidine | ADRA2C, SLC6A2, ADRA2A | ALDH1A1 1934/4885MEN1 2539/4885KMT2A 2550/4885 |
| US-20260007638-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF CLONIDINE | CHRM2, GLP1R, CHRM1 | ALDH1A1 2274/4885MEN1 948/4885KMT2A 590/4885 |
| US-20250152558-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF CLONIDINE | ADRA2C, SLC6A2, ADRA2A | ALDH1A1 1934/4885MEN1 2539/4885KMT2A 2550/4885 |
| US-20230149359-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF CLONIDINE | ADRA2C, SLC6A2, ADRA2A | ALDH1A1 1973/4885MEN1 2477/4885KMT2A 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.