SCHEMBL9249388

SCHEMBL9249388

[CH2]Cc1cc(CC=C)c(O)c(CC=C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.44
GABRB2 P47870 4/20 0.44
XDH P47989 2/20 0.41
DHFR P00374 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
GAA P10253 3/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
CNR1 P21554 2/20 0.39
CNR2 P34972 2/20 0.39
AKR1B1 P15121 2/20 0.39
ALDH1A1 P00352 1/20 0.39
ALDH2 P05091 1/20 0.39
HPGD P15428 1/20 0.39
PPARG P37231 1/20 0.39
PPARD Q03181 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
POLB P06746 2/20 0.39
ALOX5 P09917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2461750 0.86 XDH (0.48) GABRA1GABRB2XDHDHFRMEN1
SCHEMBL11660801 0.84 GABRA1 (0.45) GABRA1GABRB2XDHDHFRMEN1
SCHEMBL9489328 0.84 DHFR (0.48) GABRA1GABRB2XDHDHFRMEN1
SCHEMBL9242965 0.83 DHFR (0.42) GABRA1GABRB2XDHDHFRMEN1
SCHEMBL9287678 0.83 DHFR (0.47) GABRA1GABRB2XDHDHFRMEN1
SCHEMBL9284337 0.83 GABRA1 (0.44) GABRA1GABRB2XDHDHFRMEN1
SCHEMBL2687511 0.83 KDM4E (0.45) GABRA1GABRB2XDHDHFRMEN1
SCHEMBL9284341 0.81 DHFR (0.43) GABRA1GABRB2XDHDHFRMEN1
SCHEMBL14488339 0.81 GABRA1 (0.42) GABRA1GABRB2XDHDHFRMEN1
SCHEMBL11369315 0.81 GABRA1 (0.42) GABRA1GABRB2XDHDHFRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US claimed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US claimed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP claimed
EP-0101041-B1 ZEROVALENT NICKEL PHOSPHITE COMPLEXES BORG-WARNER CHEMICALS INC. (US) 1987-01-07 EP claimed
EP-0101042-B1 LIGHT-STABLE POLYOLEFINS BORG-WARNER CHEMICALS INC. (US) 1986-10-29 EP claimed
EP-0101992-B1 PROCESS FOR PREPARING ORGANIC NICKEL COMPLEXES BORG-WARNER CHEMICALS INC. (US) 1986-05-21 EP claimed
US-4450113-A IMPROVING ULTRAVIOLET RADIATION RESISTANCE% OF OLEFIN POLYMERS BORG-WARNER CHEMICALS, INC. (US) 1984-05-22 US claimed
EP-0101992-A1 Process for preparing organic nickel complexes BORG-WARNER CHEMICALS INC. (US) 1984-03-07 EP claimed
EP-0101042-A1 Light-stable polyolefins BORG-WARNER CHEMICALS INC. (US) 1984-02-22 EP claimed
EP-0101041-A1 Zerovalent nickel phosphite complexes BORG-WARNER CHEMICALS INC. (US) 1984-02-22 EP claimed
US-4410650-A NICKEL COMPLEX OF A PENTAERYTHRITOL PHOSPHITE BORG-WARNER CHEMICALS, INC. (US) 1983-10-18 US claimed
US-4263446-A Process for making 3-(3,5-dialkyl-4-hydroxyphenyl)propionate esters of hydroxyalkyloxamides UNIROYAL, INC. (US) 1981-04-21 US claimed
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed