Methacrylic Acid

Methacrylic Acid

SCHEMBL460950

C=C.C=C(C)C(=O)O.C=CCOC(=O)C(=C)C

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
THRB P10828 1/20 0.41
ALDH1A1 P00352 6/20 0.39
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
MAPT P10636 4/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
MEN1 O00255 2/20 0.33
MAPK1 P28482 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
HSD17B10 Q99714 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL655219 0.98 TSHR (0.45) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL250051 0.98 TSHR (0.45) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL11017971 0.96 TSHR (0.44) TSHRTHRBALDH1A1CYP3A4TDP1
Ethylene SCHEMBL460398 0.94 TSHR (0.48) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL28243084 0.92 TSHR (0.41) TSHRTHRBALDH1A1CYP3A4TDP1
Acetic Acid SCHEMBL8775549 0.92 TSHR (0.47) TSHRTHRBALDH1A1CYP3A4TDP1
Bicarbonate SCHEMBL28114546 0.92 TSHR (0.47) TSHRTHRBALDH1A1CYP3A4TDP1
Bicarbonate SCHEMBL2301694 0.92 TSHR (0.47) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL8921614 0.92
SCHEMBL1057516 0.92 TSHR (0.50) TSHRTHRBALDH1A1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US claimed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP claimed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US claimed
US-5738843-A POLYMERIZED METHACRYLATE LIQUID BINDER OPI PRODUCTS, INC. (US) 1998-04-14 US claimed
US-11203192-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2021-12-21 US disclosed
US-10844184-B2 Matte finish polyimide films and methods relating thereto DUPONT ELECTRONICS, INC. (US) 2020-11-24 US disclosed
US-20190263099-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-08-29 US disclosed
US-10336045-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2019-07-02 US disclosed
US-20180163006-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-06-14 US disclosed
US-9926415-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2018-03-27 US disclosed
US-20170174950-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2017-06-22 US disclosed
US-9631054-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2017-04-25 US disclosed
US-20110177321-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 US disclosed
WO-2011019899-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 WO disclosed
US-20110039085-A1 PIGMENTED POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 US disclosed
WO-2011017291-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-10 WO disclosed
WO-2010101822-A1 MULTILAYER FILM FOR ELECTRONIC CIRCUITRY APPLICATIONS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-10 WO disclosed
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US disclosed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP disclosed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US disclosed