Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 2/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248972 | 0.77 | CA2 (0.42) | HSD11B1 | |
| SCHEMBL9244835 | 0.75 | SLC16A3 (0.41) | SLC16A3SLC16A1KMT2AMEN1HSD11B1 | |
| Hydrochloric Acid SCHEMBL9244003 | 0.75 | SLC16A3 (0.42) | SLC16A3SLC16A1 | |
| SCHEMBL9248163 | 0.74 | SLC16A3 (0.38) | SLC16A3SLC16A1KMT2AMEN1HSD11B1 | |
| SCHEMBL9247301 | 0.73 | ADORA3 (0.43) | SLC16A3SLC16A1FFAR4 | |
| SCHEMBL27830644 | 0.73 | SLC7A5 (0.47) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL9243997 | 0.73 | SLC16A3 (0.35) | SLC16A3SLC16A1HSD11B1FFAR4 | |
| SCHEMBL31234585 | 0.72 | LDHA (0.59) | PPARAPPARGLDHA | |
| SCHEMBL8520688 | 0.72 | LDHA (0.59) | PPARAPPARGLDHA | |
| SCHEMBL4005029 | 0.72 | LDHA (0.59) | PPARAPPARGLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403953-A | Antiarthritic and -inflammatory agents | ADIR ET COMPAGNIE (FR) | 1995-04-04 | — | — | US | disclosed |