Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 11/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.38 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251166 | 0.81 | GSK3B (0.43) | TP53FFAR4ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8748105 | 0.79 | KDM4E (0.48) | CA1CA2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8747844 | 0.75 | AKR1C3 (0.47) | TP53RXRAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9251161 | 0.74 | HSD11B1 (0.30) | — | |
| SCHEMBL9247331 | 0.74 | PGR (0.31) | — | |
| SCHEMBL5084654 | 0.73 | TSHR (0.57) | CA1CA2TP53TSHRRXRA | |
| SCHEMBL20135317 | 0.73 | CA1 (0.53) | CA1CA2TP53TSHRRXRA | |
| SCHEMBL5470752 | 0.72 | TSHR (0.50) | CA1CA2TP53TSHRALDH1A1 | |
| SCHEMBL5478519 | 0.72 | TSHR (0.50) | CA1CA2TP53TSHRALDH1A1 | |
| SCHEMBL5480370 | 0.72 | TSHR (0.50) | CA1CA2TP53TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403953-A | Antiarthritic and -inflammatory agents | ADIR ET COMPAGNIE (FR) | 1995-04-04 | — | — | US | disclosed |