Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246492 | 0.83 | TSHR (0.34) | — | |
| SCHEMBL9250285 | 0.74 | CA1 (0.44) | — | |
| SCHEMBL8747895 | 0.73 | SLC16A3 (0.43) | — | |
| SCHEMBL9247301 | 0.73 | ADORA3 (0.43) | ADORA3 | |
| SCHEMBL8747723 | 0.72 | HSD11B1 (0.32) | HSD11B1ADORA3 | |
| Hydrochloric Acid SCHEMBL9244003 | 0.72 | SLC16A3 (0.42) | — | |
| SCHEMBL9245590 | 0.71 | PPARA (0.38) | — | |
| SCHEMBL9248972 | 0.71 | CA2 (0.42) | HSD11B1 | |
| SCHEMBL2231434 | 0.69 | KMT2A (0.46) | — | |
| SCHEMBL9248163 | 0.69 | SLC16A3 (0.38) | HSD11B1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403953-A | Antiarthritic and -inflammatory agents | ADIR ET COMPAGNIE (FR) | 1995-04-04 | — | — | US | disclosed |
| EP-0599732-A1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-06-01 | — | — | EP | disclosed |