Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.51 |
| ▸ | DRD3 | P35462 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253963 | 0.94 | SLC6A3 (0.55) | SLC6A2DRD3DRD2DRD4SLC6A3 | |
| SCHEMBL8643817 | 0.90 | DRD3 (0.59) | SLC6A2DRD3DRD2DRD4SLC6A3 | |
| SCHEMBL9256723 | 0.84 | DRD3 (0.54) | SLC6A2DRD3DRD2DRD4SLC6A3 | |
| SCHEMBL9257214 | 0.84 | DRD3 (0.59) | SLC6A2DRD3DRD2DRD4SLC6A3 | |
| SCHEMBL9256629 | 0.82 | DRD3 (0.51) | SLC6A2DRD3DRD2DRD4SLC6A3 | |
| SCHEMBL9250340 | 0.82 | IDO1 (0.50) | SLC6A2DRD3DRD2SLC6A3CHRM1 | |
| SCHEMBL14814326 | 0.81 | SLC6A2 (0.51) | SLC6A2DRD3DRD2DRD4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9352828 | 0.80 | SLC6A2 (0.51) | SLC6A2DRD3DRD2DRD4SLC6A3 | |
| SCHEMBL9673190 | 0.79 | CHRM1 (0.82) | SLC6A2DRD3DRD2SLC6A3CHRM1 | |
| SCHEMBL2625666 | 0.78 | SLC6A2 (0.58) | SLC6A2DRD3DRD2DRD4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | claimed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | claimed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |