Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 4/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250346 | 0.94 | SLC6A2 (0.51) | SLC6A3SLC6A2DRD3CHRM1CYP1A2 | |
| SCHEMBL9250050 | 0.82 | SLC6A3 (0.44) | SLC6A3SLC6A2DRD3CHRM1CYP1A2 | |
| SCHEMBL2092340 | 0.82 | DRD3 (0.55) | SLC6A3DRD3CYP1A2CYP2D6TSHR | |
| SCHEMBL8643817 | 0.81 | DRD3 (0.59) | SLC6A3SLC6A2DRD3CHRM1CYP1A2 | |
| SCHEMBL2096027 | 0.79 | PDE2A (0.37) | SLC6A3SLC6A2DRD3CHRM1CYP1A2 | |
| SCHEMBL6982214 | 0.79 | SLC6A3 (0.55) | SLC6A3SLC6A2DRD3CHRM1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11199043 | 0.77 | SLC6A2 (0.56) | SLC6A3SLC6A2DRD3CHRM1CYP1A2 | |
| SCHEMBL9256723 | 0.77 | DRD3 (0.54) | SLC6A3SLC6A2DRD3CHRM1CYP1A2 | |
| SCHEMBL9257214 | 0.77 | DRD3 (0.59) | SLC6A3SLC6A2DRD3CHRM1CYP1A2 | |
| SCHEMBL2625667 | 0.75 | SLC6A2 (0.64) | SLC6A3SLC6A2DRD3CHRM1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | claimed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | claimed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |