Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092340 | 0.94 | DRD3 (0.55) | DRD3MEN1MAPTKMT2ACYP2D6 | |
| SCHEMBL8643817 | 0.90 | DRD3 (0.59) | DRD3MEN1MAPTKMT2ACYP2D6 | |
| SCHEMBL9250346 | 0.84 | SLC6A2 (0.51) | DRD3CYP2D6CYP1A2TSHRDRD2 | |
| SCHEMBL9256723 | 0.84 | DRD3 (0.54) | DRD3MEN1MAPTKMT2ACYP2D6 | |
| SCHEMBL9257208 | 0.82 | IDO1 (0.51) | DRD3MEN1MAPTKMT2ACYP2D6 | |
| SCHEMBL9256629 | 0.82 | DRD3 (0.51) | DRD3MEN1MAPTKMT2ACYP2D6 | |
| SCHEMBL8537416 | 0.81 | DRD3 (0.59) | DRD3MEN1MAPTKMT2ACYP2D6 | |
| SCHEMBL9253963 | 0.77 | SLC6A3 (0.55) | DRD3CYP2D6CYP1A2TSHRDRD2 | |
| SCHEMBL9250050 | 0.77 | SLC6A3 (0.44) | DRD3CYP2D6CYP1A2TSHRDRD2 | |
| SCHEMBL9256722 | 0.76 | CYP2D6 (0.48) | DRD3MEN1MAPTKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | claimed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | claimed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |