SCHEMBL9250355

SCHEMBL9250355

O=C(C(=O)c1ccc(Oc2ccccc2Oc2ccccc2)cc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 7/20 0.60
CES1 P23141 6/20 0.60
PARP10 Q53GL7 2/20 0.55
SRD5A2 P31213 2/20 0.53
TTR P02766 2/20 0.53
CTNNB1 P35222 1/20 0.52
MEN1 O00255 1/20 0.51
RAB9A P51151 1/20 0.51
KMT2A Q03164 1/20 0.51
PGR P06401 1/20 0.49
AKR1C3 P42330 1/20 0.48
ERCC5 P28715 1/20 0.47
FEN1 P39748 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9242631 0.90 CES2 (0.68) CES2CES1PARP10SRD5A2PGR
SCHEMBL13567254 0.87 CES2 (0.71) CES2CES1PARP10SRD5A2RAB9A
SCHEMBL4189871 0.87 PARP10 (0.69) CES2CES1PARP10SRD5A2KMT2A
SCHEMBL2134251 0.87 CES2 (0.71) CES2CES1PARP10SRD5A2RAB9A
SCHEMBL9250736 0.87 CES2 (0.71) CES2CES1PARP10SRD5A2RAB9A
SCHEMBL30054718 0.86 SRD5A2 (0.66) PARP10SRD5A2MEN1RAB9AKMT2A
SCHEMBL28928525 0.86 SRD5A2 (0.66) PARP10SRD5A2MEN1RAB9AKMT2A
SCHEMBL10557155 0.86 SRD5A2 (0.71) PARP10SRD5A2TTRCTNNB1
SCHEMBL11508105 0.85 CTNNB1 (0.62) CES2CES1CTNNB1MEN1RAB9A
SCHEMBL7706043 0.83 SRD5A2 (0.68) CES2CES1PARP10SRD5A2TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0368006-B1 Copolymers containing polybenzoxazole polybenzothiazole and polybenzimidazole moieties DOW CHEMICAL CO (US) 1995-04-05 EP disclosed
US-5151489-A Block copolymers for compression molding to form fibers, films and laminates THE DOW CHEMICAL COMPANY (US) 1992-09-29 US disclosed
US-5098985-A Block copolymers for films, fibers, laminates or compression moldings THE DOW CHEMICAL COMPANY (US) 1992-03-24 US disclosed
EP-0392008-A4 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES 1991-09-04 EP disclosed
EP-0392008-A1 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1990-10-17 EP disclosed
EP-0368006-A2 Copolymers containing polybenzoxazole polybenzothiazole and polybenzimidazole moieties THE DOW CHEMICAL COMPANY (US) 1990-05-16 EP disclosed
WO-1990003995-A1 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1990-04-19 WO disclosed