Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250405 | 1.00 | HTR1A (0.31) | HTR1ADRD2HTR2ADRD3DRD1 | |
| SCHEMBL8034615 | 0.96 | — | — | |
| SCHEMBL8034627 | 0.96 | — | — | |
| SCHEMBL8034621 | 0.96 | — | — | |
| SCHEMBL9249729 | 0.88 | DRD2 (0.35) | HTR1ADRD2HTR2ADRD3DRD1 | |
| SCHEMBL9249732 | 0.88 | DRD2 (0.35) | HTR1ADRD2HTR2ADRD3DRD1 | |
| SCHEMBL9256076 | 0.87 | CCR2 (0.32) | — | |
| SCHEMBL9256069 | 0.87 | CCR2 (0.32) | — | |
| SCHEMBL8038578 | 0.87 | DRD2 (0.35) | HTR1ADRD2HTR2ADRD3DRD1 | |
| SCHEMBL8036716 | 0.85 | DRD2 (0.33) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5302317-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0315014-B1 | Halogenated benzene derivatives | HOFFMANN LA ROCHE (CH) | 1994-01-12 | — | — | EP | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0315014-A2 | Halogenated benzene derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-05-10 | — | — | EP | disclosed |