SCHEMBL9250482

SCHEMBL9250482

CC(C)(C)c1cc(CCl)cc(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
HMGCR P04035 3/20 0.39
RXRA P19793 3/20 0.37
RXRB P28702 3/20 0.37
RXRG P48443 3/20 0.37
POLB P06746 1/20 0.37
HTR1D P28221 2/20 0.37
CYP2C19 P33261 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
PON1 P27169 1/20 0.33
HTR1B P28222 1/20 0.33
BCHE P06276 3/20 0.31
ACHE P22303 3/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17393753 0.95 GABRA1 (0.40) GABRA1GABRB2HMGCRRXRARXRB
SCHEMBL23801960 0.84 GABRA1 (0.33) GABRA1GABRB2HMGCRPOLBHTR1D
SCHEMBL6324150 0.80 GABRA1 (0.42) GABRA1GABRB2HMGCRRXRARXRB
SCHEMBL14760885 0.80 HMGCR (0.31) GABRA1GABRB2HMGCR
SCHEMBL962215 0.79 GABRA1 (0.52) GABRA1GABRB2HMGCRRXRARXRB
SCHEMBL20472890 0.78 GABRA1 (0.50) GABRA1GABRB2HMGCRRXRARXRB
SCHEMBL8213794 0.78 GABRA1 (0.50) GABRA1GABRB2HMGCRRXRARXRB
SCHEMBL10537645 0.77 ACHE (0.43) RXRARXRBCYP2C19PON1BCHE
SCHEMBL93161 0.76 GABRA1 (0.69) GABRA1GABRB2HMGCRRXRARXRB
SCHEMBL3262493 0.76 GABRA1 (0.48) GABRA1GABRB2HMGCRRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119330805-A Preparation method of 3, 5-di-tert-butyl benzyl alcohol 宁夏忠同生物科技有限公司 2025-01-21 CN disclosed
US-5420343-A ANTIINFLAMMATORY AGENTS; CYCLOOXYGENASE INHIBITORS G. D. SEARLE & CO. (US) 1995-05-30 US disclosed