Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.50 |
| ▸ | RARA | P10276 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248073 | 0.87 | GAA (0.43) | ITGB3ITGA2BRARARARBRARG | |
| SCHEMBL9257438 | 0.76 | ITGB3 (0.46) | ITGB3ITGA2BNQO2WDR5HDAC6 | |
| SCHEMBL9253949 | 0.75 | ITGB3 (0.52) | ITGB3ITGA2BHDAC6MAPTMEN1 | |
| SCHEMBL9252063 | 0.74 | S1PR1 (0.45) | ITGB3ITGA2B | |
| SCHEMBL3669304 | 0.71 | RARB (0.54) | RARARARBRARGMAPTGAA | |
| SCHEMBL9252600 | 0.71 | ITGB3 (0.49) | ITGB3ITGA2BNQO2TMPRSS15GAA | |
| SCHEMBL9251460 | 0.70 | NQO2 (0.56) | ITGB3ITGA2BNQO2WDR5TMPRSS15 | |
| SCHEMBL9250114 | 0.70 | ITGB3 (0.58) | ITGB3ITGA2BNQO2TMPRSS15PRSS1 | |
| SCHEMBL9252751 | 0.70 | PRMT1 (0.51) | ITGB3ITGA2BTMPRSS15MAPTGAA | |
| SCHEMBL9251513 | 0.69 | S1PR1 (0.44) | ITGB3ITGA2BTMPRSS15GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |