Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250114 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BPRSS1TMPRSS15CSNK2A2 | |
| SCHEMBL9252063 | 0.86 | S1PR1 (0.45) | ITGB3ITGA2B | |
| SCHEMBL9254531 | 0.85 | TMPRSS15 (0.43) | ITGB3ITGA2BPRSS1TMPRSS15CSNK2A2 | |
| SCHEMBL9251513 | 0.83 | S1PR1 (0.44) | ITGB3ITGA2BPRSS1TMPRSS15FFAR1 | |
| SCHEMBL9257176 | 0.82 | CSNK2A2 (0.43) | ITGB3ITGA2BPRSS1TMPRSS15CSNK2A2 | |
| SCHEMBL24073031 | 0.79 | GLS (0.48) | CSNK2A2CSNK2A1HDAC6 | |
| SCHEMBL9247290 | 0.79 | TMPRSS15 (0.35) | ITGB3ITGA2BTMPRSS15CSNK2A2CSNK2A1 | |
| SCHEMBL9250705 | 0.76 | ITGB3 (0.50) | ITGB3ITGA2BPRSS1TMPRSS15HDAC6 | |
| SCHEMBL9254086 | 0.76 | F2 (0.39) | ITGB3ITGA2BPRSS1CSNK2A2CSNK2A1 | |
| SCHEMBL1566839 | 0.76 | KDM4E (0.53) | CSNK2A2CSNK2A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | claimed |
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |