Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.51 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253071 | 0.86 | NQO2 (0.56) | NQO2TMPRSS15PRSS1F2F10 | |
| SCHEMBL9251460 | 0.84 | NQO2 (0.56) | NQO2RPS6KB2TMPRSS15PRSS1 | |
| SCHEMBL14340893 | 0.80 | RPS6KB2 (0.64) | NQO2RPS6KB2HPGD | |
| SCHEMBL9254531 | 0.76 | TMPRSS15 (0.43) | NQO2HPGDTMPRSS15PRSS1F2 | |
| SCHEMBL9257420 | 0.75 | F2 (0.48) | NQO2TMPRSS15PRSS1F2F10 | |
| SCHEMBL9254014 | 0.75 | NQO2 (0.55) | NQO2HPGDTMPRSS15PRSS1 | |
| SCHEMBL9253124 | 0.75 | F2 (0.45) | TMPRSS15PRSS1F2F10 | |
| SCHEMBL9248073 | 0.74 | GAA (0.43) | TMPRSS15 | |
| Hydrochloric Acid SCHEMBL9254391 | 0.74 | ST14 (0.54) | PRSS1F2F10 | |
| SCHEMBL9250170 | 0.73 | NQO2 (0.61) | NQO2HPGDTMPRSS15PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |