Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255636 | 0.88 | TMPRSS15 (0.39) | TMPRSS15F2F10PRSS1ITGB3 | |
| SCHEMBL9253124 | 0.88 | F2 (0.45) | TMPRSS15CSNK2A2CSNK2A1F2F10 | |
| SCHEMBL9257176 | 0.87 | CSNK2A2 (0.43) | TMPRSS15CSNK2A2CSNK2A1F2F10 | |
| SCHEMBL9250922 | 0.87 | AHR (0.39) | TMPRSS15HPGDSMN1; SMN2 | |
| SCHEMBL9257116 | 0.86 | CSNK2A2 (0.42) | CSNK2A2CSNK2A1HDAC6GAAMAPT | |
| SCHEMBL9257438 | 0.85 | ITGB3 (0.46) | TMPRSS15CSNK2A2CSNK2A1F2PRSS1 | |
| SCHEMBL9247290 | 0.84 | TMPRSS15 (0.35) | TMPRSS15CSNK2A2CSNK2A1F2F10 | |
| SCHEMBL9254086 | 0.81 | F2 (0.39) | CSNK2A2CSNK2A1F2F10PRSS1 | |
| SCHEMBL9256954 | 0.80 | CYP11B1 (0.47) | MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9257782 | 0.79 | CSNK2A2 (0.39) | CSNK2A2CSNK2A1HDAC6GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | claimed |
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |