Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 3/20 | 0.50 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.50 |
| ▸ | NPC1L1 | Q9UHC9 | 7/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | CRYAB | P02511 | 1/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250491 | 0.91 | CDC25A (0.48) | NPC1L1VDRUSP2 | |
| SCHEMBL9250800 | 0.82 | NPC1L1 (0.56) | OSBPOSBP2NPC1L1NR1H3CRYAB | |
| SCHEMBL11651241 | 0.82 | NFKB1 (0.43) | OSBPOSBP2NPC1L1NFKB1NFKB2 | |
| SCHEMBL11651242 | 0.82 | NFKB1 (0.43) | OSBPOSBP2NPC1L1NFKB1NFKB2 | |
| SCHEMBL25339736 | 0.77 | OSBP (0.57) | OSBPOSBP2NPC1L1NR1H3CRYAB | |
| SCHEMBL25338039 | 0.77 | OSBP (0.57) | OSBPOSBP2NPC1L1NR1H3CRYAB | |
| SCHEMBL25338037 | 0.77 | OSBP (0.57) | OSBPOSBP2NPC1L1NR1H3CRYAB | |
| SCHEMBL25339737 | 0.77 | OSBP (0.57) | OSBPOSBP2NPC1L1NR1H3CRYAB | |
| SCHEMBL9250803 | 0.76 | NPC1L1 (0.46) | OSBPOSBP2NPC1L1NFKB1NFKB2 | |
| SCHEMBL18942518 | 0.76 | NPC1L1 (0.71) | OSBPOSBP2NPC1L1NR1H3CRYAB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395953-A | Method of preparing hydrindane compounds and hydrindane-related compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1995-03-07 | — | — | US | disclosed |
| EP-0594229-A1 | Method of preparing hydrindane compounds and hydrindane-related compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1994-04-27 | — | — | EP | disclosed |