Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 8/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 3/20 | 0.47 |
| ▸ | FNTB | P49356 | 3/20 | 0.47 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | VDR | P11473 | 1/20 | 0.45 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250798 | 0.91 | OSBP (0.50) | USP2NPC1L1VDR | |
| Acebrochol SCHEMBL9250494 | 0.81 | NPC1L1 (0.56) | CDC25APOLA1FNTAFNTBUSP2 | |
| Acebrochol SCHEMBL1006383 | 0.81 | NPC1L1 (0.56) | CDC25APOLA1FNTAFNTBUSP2 | |
| Acebrochol SCHEMBL30009744 | 0.81 | NPC1L1 (0.56) | CDC25APOLA1FNTAFNTBUSP2 | |
| SCHEMBL11318380 | 0.80 | CDC25A (0.51) | CDC25APOLA1FNTAFNTBCDC25B | |
| SCHEMBL11318351 | 0.80 | CDC25A (0.51) | CDC25APOLA1FNTAFNTBCDC25B | |
| SCHEMBL11651242 | 0.79 | NFKB1 (0.43) | CDC25APOLA1FNTAFNTBUSP2 | |
| SCHEMBL11651241 | 0.79 | NFKB1 (0.43) | CDC25APOLA1FNTAFNTBUSP2 | |
| SCHEMBL4739368 | 0.77 | CDC25A (0.57) | CDC25APOLA1FNTAFNTBCDC25B | |
| SCHEMBL4740626 | 0.77 | CDC25A (0.57) | CDC25APOLA1FNTAFNTBCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395953-A | Method of preparing hydrindane compounds and hydrindane-related compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1995-03-07 | — | — | US | disclosed |
| EP-0594229-A1 | Method of preparing hydrindane compounds and hydrindane-related compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1994-04-27 | — | — | EP | disclosed |