Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.37 |
| ▸ | NQO2 | P16083 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251411 | 0.90 | ADORA2A (0.38) | F2NQO2CYP3A4ITGB3ITGA2B | |
| SCHEMBL9253931 | 0.89 | ITGB3 (0.35) | F2NQO2ITGB3ITGA2B | |
| SCHEMBL9250640 | 0.84 | NQO2 (0.39) | F2NQO2ITGB3ITGA2B | |
| SCHEMBL9251548 | 0.79 | ADORA2A (0.35) | F2NQO2ITGB3ITGA2BADORA2A | |
| SCHEMBL9259667 | 0.76 | ITGB3 (0.39) | NQO2ITGB3ITGA2B | |
| SCHEMBL9257715 | 0.74 | NQO2 (0.35) | F2NQO2ITGB3ITGA2BADORA2A | |
| SCHEMBL9254490 | 0.72 | F10 (0.38) | ITGB3ITGA2B | |
| SCHEMBL9251855 | 0.71 | PPARD (0.46) | ITGB3ITGA2B | |
| SCHEMBL9255778 | 0.70 | ITGB3 (0.37) | NQO2ITGB3ITGA2B | |
| SCHEMBL9256974 | 0.70 | ITGB3 (0.51) | F2NQO2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |