Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251983 | 0.90 | HTT (0.43) | PPARDITGB3ITGA2BPPARAGRK6 | |
| SCHEMBL9254301 | 0.88 | ITGB3 (0.42) | PPARDITGB3ITGA2BMPO | |
| SCHEMBL9254081 | 0.86 | F10 (0.41) | PPARDITGB3ITGA2BMPO | |
| SCHEMBL9251475 | 0.85 | ITGB3 (0.41) | PPARDITGB3ITGA2BPPARAMPO | |
| SCHEMBL9254458 | 0.83 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL9257540 | 0.79 | PLAU (0.39) | ITGB3ITGA2B | |
| SCHEMBL9251306 | 0.77 | HTT (0.37) | ITGB3ITGA2B | |
| SCHEMBL9256124 | 0.76 | HTT (0.35) | ITGB3ITGA2B | |
| SCHEMBL9255039 | 0.76 | S1PR1 (0.43) | ITGB3ITGA2B | |
| SCHEMBL9255915 | 0.74 | ITGB3 (0.44) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399636-A | Bound to inorganic support, olefin polymerization catalysts | PHILLIPS PETROLEUM COMPANY (US) | 1995-03-21 | — | — | US | claimed |
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |