Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253132 | 1.00 | ITGB3 (0.51) | ITGB3ITGA2BCHEK2F2F10 | |
| SCHEMBL9568559 | 0.86 | F2 (0.41) | ITGB3ITGA2BCHEK2F2F10 | |
| SCHEMBL9257084 | 0.86 | F2 (0.41) | ITGB3ITGA2BCHEK2F2F10 | |
| Hydrochloric Acid SCHEMBL9254356 | 0.85 | F2 (0.40) | ITGB3ITGA2BCHEK2F2F10 | |
| SCHEMBL9258365 | 0.85 | NQO2 (0.38) | ITGB3ITGA2BPRSS1TMPRSS15FFAR1 | |
| SCHEMBL9254490 | 0.83 | F10 (0.38) | ITGB3ITGA2BF10 | |
| SCHEMBL9255778 | 0.83 | ITGB3 (0.37) | ITGB3ITGA2BCHEK2F10PRSS1 | |
| SCHEMBL9259655 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2BF2PRSS1TMPRSS15 | |
| SCHEMBL9254802 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BPRSS1TMPRSS15NQO2 | |
| SCHEMBL9254922 | 0.80 | GRK6 (0.42) | ITGB3ITGA2BFFAR1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | claimed |
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |