Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.38 |
| ▸ | MTOR | P42345 | 5/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896518 | 0.82 | POLB (0.42) | GAAKDM4EHTTALDH1A1PIK3CA | |
| SCHEMBL9660846 | 0.81 | GAA (0.42) | GAAKDM4EHTTALDH1A1PIK3CA | |
| SCHEMBL9250447 | 0.69 | HTT (0.57) | GAAKDM4EHTTALDH1A1PIK3CA | |
| SCHEMBL9869002 | 0.69 | ALDH1A1 (0.37) | GAAKDM4EHTTALDH1A1PIK3CA | |
| SCHEMBL9250855 | 0.68 | GAA (0.35) | GAAKDM4EHTTALDH1A1PIK3CA | |
| SCHEMBL9473324 | 0.68 | CYP11B2 (0.53) | GAAKDM4EHTTALDH1A1PIK3CA | |
| SCHEMBL9168729 | 0.67 | POLB (0.35) | GAAKDM4EHTTALDH1A1PIK3CA | |
| SCHEMBL27309896 | 0.66 | POLB (0.39) | GAAKDM4EHTTALDH1A1MAPK1 | |
| SCHEMBL7902694 | 0.66 | MAPK1 (0.34) | GAAKDM4EHTTALDH1A1MAPK1 | |
| SCHEMBL9254724 | 0.66 | PIK3CA (0.35) | GAAKDM4EHTTALDH1A1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425283-B1 | Novel triazolyl hydrazide derivatives and process for their preparation | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-05-10 | — | — | EP | disclosed |
| US-5225410-A | Antiangina, antiulcer agents | EGIS GYOGYSZERGYAR (HU) | 1993-07-06 | — | — | US | disclosed |
| EP-0425283-A2 | Novel triazolyl hydrazide derivatives and process for their preparation | EGIS GYOGYSZERGYAR (HU) | 1991-05-02 | — | — | EP | disclosed |