Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | BCL9 | O00512 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14642800 | 0.91 | TAAR1 (0.46) | PRMT6KDRRPS6KA3CYP2A6CYP2E1 | |
| SCHEMBL4901701 | 0.87 | PRMT6 (0.43) | PRMT6KDRCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9169905 | 0.86 | TSHR (0.42) | PRMT6KDRCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9255273 | 0.86 | PRMT6 (0.40) | PRMT6KDRCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9259837 | 0.85 | PRMT6 (0.40) | PRMT6KDRCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9259584 | 0.84 | LTB4R (0.43) | PRMT6KDRCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9255428 | 0.82 | TSHR (0.45) | PRMT6KDRPDGFRBPDGFRAKDM4E | |
| SCHEMBL9174629 | 0.81 | PRMT6 (0.39) | PRMT6KDRCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9257607 | 0.81 | ALDH1A1 (0.47) | PRMT6KDRCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9251814 | 0.81 | TSHR (0.46) | PRMT6KDRKDM4EMAPK1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |