Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 7/20 | 0.41 |
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568473 | 1.00 | MAPT (0.47) | MAPTKMT2AMEN1LMNAHTT | |
| SCHEMBL9254628 | 0.87 | ITGB3 (0.57) | MAPTKMT2AMEN1LMNAHTT | |
| SCHEMBL9254812 | 0.87 | ITGB3 (0.57) | MAPTKMT2AMEN1LMNAHTT | |
| SCHEMBL9257414 | 0.85 | TMPRSS15 (0.39) | MAPTKMT2AMEN1LMNAHTT | |
| SCHEMBL9258402 | 0.82 | MAPT (0.48) | MAPTKMT2AMEN1LMNAHTT | |
| Hydrochloric Acid SCHEMBL7275280 | 0.79 | ITGB3 (0.42) | MAPTKMT2AMEN1SMN1; SMN2ITGB3 | |
| Hydrochloric Acid SCHEMBL7274067 | 0.79 | ITGB3 (0.42) | MAPTKMT2AMEN1SMN1; SMN2ITGB3 | |
| SCHEMBL9258658 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL9256866 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL9253224 | 0.77 | MAPT (0.47) | MAPTKMT2AMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |