Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | STK10 | O94804 | 2/20 | 0.36 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930414 | 0.84 | CYP3A4 (0.44) | GSK3BGAAKDM4EALDH1A1HPGD | |
| Water SCHEMBL8678456 | 0.81 | DDB1 (0.45) | GSK3BGAAKDM4EALDH1A1HPGD | |
| SCHEMBL7399139 | 0.79 | DDB1 (0.46) | GSK3BGAAKDM4EALDH1A1HPGD | |
| SCHEMBL2701829 | 0.79 | GSK3B (0.42) | GSK3BGAAKDM4EALDH1A1HPGD | |
| SCHEMBL8598409 | 0.77 | PSEN1 (0.43) | GSK3BNPC1RAB9ASTK10SLK | |
| SCHEMBL11064554 | 0.76 | KCNA3 (0.40) | GSK3BRAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL10776993 | 0.76 | CDK2 (0.43) | GSK3BRAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL7648225 | 0.76 | CYP2A6 (0.43) | GSK3BGAAKDM4EALDH1A1HPGD | |
| SCHEMBL28099802 | 0.76 | GSK3B (0.50) | GSK3BGAAKDM4EALDH1A1HPGD | |
| SCHEMBL262473 | 0.76 | GSK3B (0.50) | GSK3BGAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446048-A | Immunosuppresants, antiinflammatory agent, fungicides, antitumor agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-08-29 | — | — | US | disclosed |
| US-5373014-A | Antibody inhibitor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-12-13 | — | — | US | disclosed |