Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590482 | 0.81 | TSHR (0.43) | MAPTTDP1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9251276 | 0.78 | LMNA (0.40) | MAPTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL7597803 | 0.75 | TSHR (0.57) | MAPTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL7596479 | 0.71 | TSHR (0.52) | MAPTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL29874217 | 0.70 | MAPK1 (0.70) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL265584 | 0.70 | MAPK1 (0.70) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL7596587 | 0.69 | NPC1 (0.43) | TDP1LMNAKMT2ASMN1; SMN2SCN4A | |
| SCHEMBL7591557 | 0.69 | NPC1 (0.43) | TDP1LMNAKMT2ASMN1; SMN2SCN4A | |
| SCHEMBL8181879 | 0.69 | SCN4A (0.44) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL8195071 | 0.69 | SCN4A (0.44) | MAPTMAPK1TDP1L3MBTL1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387567-A | An additional polymerization catalysts consisting of a metal compounds selected from zirconium, titanium, hafnium and organosilane compound; molecular weight controller for broad molecular weight distribution | NIPPON OIL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |