Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PIR | O00625 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251289 | 0.78 | MAPT (0.41) | LMNAMAPTKMT2APOLBNPSR1 | |
| SCHEMBL7590472 | 0.77 | ACHE (0.48) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL7597803 | 0.75 | TSHR (0.57) | LMNAMAPTKMT2AGAACYP2C19 | |
| SCHEMBL7596479 | 0.71 | TSHR (0.52) | LMNAMAPTKMT2AGAACYP2C19 | |
| SCHEMBL128703 | 0.70 | LMNA (0.67) | LMNAMAPTGAAARCYP2C19 | |
| SCHEMBL8181876 | 0.69 | LMNA (0.42) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL8195068 | 0.69 | LMNA (0.42) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL7597771 | 0.69 | LTA4H (0.45) | CYP2C19TSHRL3MBTL1TDP1MAOA | |
| SCHEMBL8319953 | 0.68 | TSHR (0.48) | LMNAMAPTKMT2AGAACYP2C19 | |
| SCHEMBL7592989 | 0.67 | TSHR (0.52) | LMNAMAPTKMT2AGAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387567-A | An additional polymerization catalysts consisting of a metal compounds selected from zirconium, titanium, hafnium and organosilane compound; molecular weight controller for broad molecular weight distribution | NIPPON OIL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |