Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43375 | 0.88 | — | — | |
| Ethylene Glycol SCHEMBL6557377 | 0.86 | TSHR (0.57) | TSHRALDH1A1TP53CAMK2AGPR84 | |
| 1,4-Butanediol SCHEMBL28048097 | 0.86 | ALDH1A1 (0.48) | TSHRALDH1A1TP53CAMK2AGPR84 | |
| SCHEMBL1405635 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL9195017 | 0.84 | — | — | |
| SCHEMBL11414863 | 0.84 | — | — | |
| Ethylene Glycol SCHEMBL6557487 | 0.83 | TSHR (0.62) | TSHRALDH1A1TP53CAMK2AGPR84 | |
| Ethylene Glycol SCHEMBL27514008 | 0.79 | TSHR (0.50) | TSHRALDH1A1TP53CAMK2AGPR84 | |
| Ethylene Glycol SCHEMBL5133455 | 0.79 | — | — | |
| SCHEMBL3872235 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634916-A1 | METHOD AND MEANS FOR PREVENTING SECONDARY CATARACT | Pharmacia & Upjohn Aktiebolag (SE) | 1995-01-25 | — | — | EP | claimed |
| US-5375611-A | Method for preventing secondary cataract | PHARMACIA AB (SE) | 1994-12-27 | — | — | US | claimed |
| WO-1994016648-A1 | METHOD AND MEANS FOR PREVENTING SECONDARY CATARACT | PHARMACIA AB (SE) | 1994-08-04 | — | — | WO | claimed |