Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251433 | 0.88 | ITGB3 (0.42) | ITGB3ITGA2BENPP2ALDH1A1RAB9A | |
| SCHEMBL9253949 | 0.76 | ITGB3 (0.52) | ITGB3ITGA2BLMNAALDH1A1RAB9A | |
| SCHEMBL21916047 | 0.74 | NAMPT (0.36) | ITGB3ITGA2BENPP2BCHE | |
| SCHEMBL7826728 | 0.72 | LOXL2 (0.64) | LMNAALDH1A1RAB9AHDAC3HDAC4 | |
| SCHEMBL2229318 | 0.71 | LMNA (0.57) | LMNAALDH1A1RAB9AL3MBTL1HDAC3 | |
| SCHEMBL9257627 | 0.69 | HDAC3 (0.44) | ENPP2ALDH1A1RAB9AL3MBTL1HDAC3 | |
| SCHEMBL21495108 | 0.67 | LOXL2 (0.65) | LMNAALDH1A1RAB9AL3MBTL1HDAC3 | |
| SCHEMBL6000151 | 0.66 | GCGR (0.41) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9408042 | 0.65 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1RAB9AHDAC3 | |
| SCHEMBL27025956 | 0.65 | NOTUM (0.39) | LMNAALDH1A1RAB9AHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |