Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 7/20 | 0.64 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 2/20 | 0.48 |
| ▸ | VDR | P11473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2250938 | 0.87 | HCAR3 (0.68) | HCAR3CDC25BALDH1A1L3MBTL1THRA | |
| SCHEMBL9248878 | 0.85 | HCAR3 (0.59) | HCAR3ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL22382403 | 0.85 | HCAR3 (0.64) | HCAR3CDC25BALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL16673894 | 0.84 | LMNA (0.56) | HCAR3CDC25BALDH1A1NPC1RAB9A | |
| SCHEMBL7979954 | 0.84 | HCAR3 (0.67) | HCAR3CDC25BALDH1A1NPC1RAB9A | |
| SCHEMBL5378190 | 0.83 | HCAR3 (0.69) | HCAR3CDC25BALDH1A1MAPTHTT | |
| SCHEMBL9247817 | 0.83 | HCAR3 (0.71) | HCAR3ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9254780 | 0.82 | KAT2B (0.56) | HCAR3ALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL9248816 | 0.82 | MAPT (0.58) | HCAR3ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2652097 | 0.82 | GCG (0.59) | ALDH1A1SMN1; SMN2NPC1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |