Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 9/20 | 0.67 |
| ▸ | CDC25B | P30305 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417655 | 0.89 | HCAR3 (0.51) | HCAR3CDC25BHTTALDH1A1MAPT | |
| SCHEMBL2339865 | 0.89 | HCAR3 (0.74) | HCAR3HTTALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2250938 | 0.86 | HCAR3 (0.68) | HCAR3CDC25BHTTALDH1A1MAPT | |
| SCHEMBL2253159 | 0.85 | HCAR3 (0.74) | HCAR3CDC25BHTTALDH1A1MAPT | |
| SCHEMBL22382403 | 0.84 | HCAR3 (0.64) | HCAR3CDC25BHTTALDH1A1MAPT | |
| SCHEMBL9251399 | 0.84 | HCAR3 (0.64) | HCAR3CDC25BHTTALDH1A1MAPT | |
| SCHEMBL2245658 | 0.83 | HCAR3 (0.59) | HCAR3CDC25BHTTALDH1A1MAPT | |
| SCHEMBL23873645 | 0.82 | HCAR3 (0.55) | HCAR3CDC25BHTTALDH1A1MAPT | |
| SCHEMBL27268253 | 0.82 | HCAR3 (0.70) | HCAR3CDC25BHTTALDH1A1MAPT | |
| SCHEMBL3116351 | 0.82 | ALDH1A1 (0.50) | HCAR3HTTALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104356022-B | A kind of synthetic method of N-methyl-4-(methylamino)-3-nitrobenzamide | 上海应用技术学院 | 2016-06-08 | — | — | CN | disclosed |
| CN-104356022-A | Synthetic method of N-methyl-4-(methyl amino)-3-nitrobenzamide | SHANGHAI INST TECHNOLOGY | 2015-02-18 | — | — | CN | disclosed |
| US-8377923-B2 | Triazole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8377923-B2 | Triazole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-05-05 | — | — | US | disclosed |
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-05-05 | — | — | US | disclosed |
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | HSD11B1, HSD11B2, HSD3B1 | HCAR3 765/4885CDC25B 4557/4885HTT 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.