Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2684241 | 0.86 | HCAR3 (0.55) | POLBMAPK1MAPTLMNAGALR2 | |
| Hydrochloric Acid SCHEMBL9251447 | 0.85 | HCAR3 (0.54) | POLBMAPK1MAPTLMNAGALR2 | |
| Hydrochloric Acid SCHEMBL9251451 | 0.85 | HCAR3 (0.54) | POLBMAPK1MAPTLMNAGALR2 | |
| SCHEMBL6775498 | 0.84 | MAPT (0.65) | POLBMAPK1MAPTLMNAGALR2 | |
| SCHEMBL2248162 | 0.82 | KMT2A (0.52) | POLBMAPK1MAPTLMNAGALR2 | |
| SCHEMBL30305536 | 0.78 | VCAM1 (0.45) | POLBMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL2368685 | 0.78 | VCAM1 (0.45) | POLBMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL6832051 | 0.78 | POLB (0.50) | POLBMAPK1MAPTLMNAGALR2 | |
| SCHEMBL2303103 | 0.76 | LMNA (0.42) | POLBMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL9251220 | 0.76 | JAK2 (0.42) | POLBMAPK1MAPTLMNAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |