Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 18/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | CCKAR | P32238 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542118 | 0.91 | CCKBR (0.77) | CCKBRKCNH2CCKAR | |
| SCHEMBL9699970 | 0.87 | CCKBR (0.71) | CCKBR | |
| SCHEMBL9303173 | 0.86 | CCKBR (0.71) | CCKBR | |
| SCHEMBL9422497 | 0.86 | CCKBR (0.53) | CCKBRKCNH2CCKAR | |
| SCHEMBL8543069 | 0.81 | CCKBR (0.62) | CCKBRKCNH2CCKAR | |
| SCHEMBL8546195 | 0.80 | CCKBR (0.64) | CCKBRKCNH2CCKAR | |
| SCHEMBL8547291 | 0.80 | CCKBR (0.62) | CCKBRCCKAR | |
| SCHEMBL9545575 | 0.79 | CCKBR (0.74) | CCKBRKCNH2CCKAR | |
| SCHEMBL8540475 | 0.79 | CCKBR (0.51) | CCKBRCCKAR | |
| SCHEMBL9573642 | 0.79 | CCKBR (0.62) | CCKBRKCNH2CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451582-A | Cholecystokinins and gastrin receptor antagonists | MERCK SHARP & DOHME LTD. (GB) | 1995-09-19 | — | — | US | claimed |
| WO-1993017011-A1 | BENZODIAZEPINE DERIVATIVES, AS CCK AND GASTRIN ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1993-09-02 | — | — | WO | claimed |
| US-5451582-A | Cholecystokinins and gastrin receptor antagonists | MERCK SHARP & DOHME LTD. (GB) | 1995-09-19 | — | — | US | disclosed |