Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 19/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699970 | 0.99 | CCKBR (0.71) | CCKBR | |
| SCHEMBL9301863 | 0.90 | CCKBR (0.62) | CCKBR | |
| SCHEMBL9701137 | 0.89 | CCKBR (0.57) | CCKBR | |
| SCHEMBL7553620 | 0.89 | CCKBR (0.58) | CCKBR | |
| SCHEMBL7553612 | 0.89 | CCKBR (0.58) | CCKBR | |
| SCHEMBL9301212 | 0.88 | CCKBR (0.56) | CCKBR | |
| SCHEMBL9278492 | 0.88 | CCKBR (0.76) | CCKBR | |
| SCHEMBL9302443 | 0.88 | CCKBR (0.55) | CCKBR | |
| SCHEMBL9251487 | 0.86 | CCKBR (0.62) | CCKBR | |
| SCHEMBL9271462 | 0.86 | CCKBR (0.71) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | claimed |
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | disclosed |