Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 5/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571178 | 0.89 | MAPT (0.39) | PARP1ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL7326004 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9251552 | 0.75 | PARP1 (0.46) | PARP1ALDH1A1SMN1; SMN2PLAUL3MBTL1 | |
| SCHEMBL9246050 | 0.74 | HDAC6 (0.40) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9247338 | 0.70 | MAPT (0.38) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7259712 | 0.69 | PARP1 (0.47) | PARP1ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL26799644 | 0.69 | TDP1 (0.58) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7259038 | 0.68 | RAB9A (0.47) | PARP1ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23222980 | 0.68 | TDP1 (0.57) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5834916 | 0.67 | ALDH1A1 (0.68) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |