Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | MASP2 | O00187 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505230 | 0.76 | DHODH (0.63) | PARP1DHODHHDAC1HDAC6CHEK2 | |
| SCHEMBL8407251 | 0.75 | SRD5A2 (0.48) | MASP2SMN1; SMN2KMT2A | |
| SCHEMBL9251561 | 0.75 | PARP1 (0.43) | PARP1SMN1; SMN2PLAUL3MBTL1ALDH1A1 | |
| SCHEMBL8363489 | 0.74 | NPC1 (0.50) | MASP2SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5845871 | 0.73 | NR4A1 (0.51) | MASP2SMN1; SMN2PLAUKMT2A | |
| SCHEMBL7276193 | 0.73 | LMNA (0.55) | MASP2SMN1; SMN2KMT2A | |
| SCHEMBL8949220 | 0.71 | XDH (0.47) | MASP2SMN1; SMN2PLAUATMKMT2A | |
| SCHEMBL10942377 | 0.71 | LMNA (0.59) | MASP2SMN1; SMN2PLAUKMT2A | |
| SCHEMBL7437216 | 0.71 | ALDH1A1 (0.59) | SMN1; SMN2ATML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9247334 | 0.71 | PTGDR2 (0.40) | MASP2SMN1; SMN2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |