Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248820 | 0.89 | HCAR3 (0.50) | ALDH1A1HCAR3LMNAMAPTCASP6 | |
| SCHEMBL9251143 | 0.78 | HCAR3 (0.48) | ALDH1A1HCAR3LMNAMAPTCASP6 | |
| SCHEMBL9254786 | 0.77 | HCAR3 (0.51) | HCAR3LMNACASP6KDM4E | |
| SCHEMBL9248881 | 0.76 | HCAR3 (0.50) | HCAR3LMNACASP6KDM4E | |
| SCHEMBL9252433 | 0.74 | BLM (0.45) | ALDH1A1HCAR3LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9247821 | 0.74 | HCAR3 (0.57) | HCAR3LMNAMAPTCASP6GAA | |
| SCHEMBL9251405 | 0.73 | HCAR3 (0.64) | HCAR3LMNACASP6KDM4E | |
| Hydrochloric Acid SCHEMBL9246058 | 0.71 | MAPT (0.62) | ALDH1A1HCAR3LMNAMAPTSMN1; SMN2 | |
| SCHEMBL31612034 | 0.69 | HCAR3 (0.68) | ALDH1A1HCAR3LMNAMAPTCASP6 | |
| SCHEMBL9246078 | 0.69 | HCAR3 (0.47) | ALDH1A1HCAR3LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |