Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246078 | 0.90 | HCAR3 (0.47) | HCAR3KMT2APKMKDM4EGLA | |
| SCHEMBL9248820 | 0.86 | HCAR3 (0.50) | HCAR3KMT2APKMKDM4EGLA | |
| SCHEMBL9254786 | 0.86 | HCAR3 (0.51) | HCAR3KDM4EGLALMNACASP6 | |
| SCHEMBL9247821 | 0.86 | HCAR3 (0.57) | HCAR3LMNACASP6MAPTTSHR | |
| SCHEMBL9248881 | 0.85 | HCAR3 (0.50) | HCAR3KDM4EGLALMNACASP6 | |
| SCHEMBL9252433 | 0.81 | BLM (0.45) | HCAR3KMT2APKMKDM4EALDH1A1 | |
| SCHEMBL9251600 | 0.78 | ALDH1A1 (0.50) | HCAR3KDM4EALDH1A1LMNACASP6 | |
| Hydrochloric Acid SCHEMBL9246058 | 0.78 | MAPT (0.62) | HCAR3KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9251077 | 0.78 | HCAR3 (0.43) | HCAR3KMT2AKDM4EGLALMNA | |
| SCHEMBL9245382 | 0.77 | HCAR3 (0.53) | HCAR3SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |