Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9254154 | 0.90 | THRB (0.44) | BLML3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL9248820 | 0.82 | HCAR3 (0.50) | ALDH1A1MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL9251143 | 0.81 | HCAR3 (0.48) | ALDH1A1MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL9251077 | 0.81 | HCAR3 (0.43) | LMNAHCAR3MEN1KMT2AKDM4E | |
| SCHEMBL9254786 | 0.78 | HCAR3 (0.51) | LMNAHCAR3KDM4E | |
| SCHEMBL9248881 | 0.77 | HCAR3 (0.50) | LMNAHCAR3KDM4E | |
| SCHEMBL9247821 | 0.75 | HCAR3 (0.57) | MAPTLMNAGAATHRBHCAR3 | |
| SCHEMBL9251600 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL9246078 | 0.72 | HCAR3 (0.47) | ALDH1A1MAPTLMNAPKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9246058 | 0.72 | MAPT (0.62) | ALDH1A1MAPTLMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |