Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166877 | 0.85 | KDM4C (0.51) | MTNR1AKDM4CFAAHALKBH1POLB | |
| SCHEMBL9160573 | 0.80 | MTNR1A (0.56) | MTNR1AKDM4CFAAH | |
| SCHEMBL1011204 | 0.77 | MTNR1A (0.82) | MTNR1AKDM4C | |
| SCHEMBL9251693 | 0.76 | MTNR1A (0.52) | MTNR1AKDM4CHTR2AHTR2CFAAH | |
| SCHEMBL3402977 | 0.76 | KDM4C (0.50) | MTNR1AKDM4CFAAHALKBH1POLB | |
| SCHEMBL28567024 | 0.75 | MTNR1A (0.48) | MTNR1AKDM4CFAAHALKBH1POLB | |
| SCHEMBL3430852 | 0.75 | MTNR1A (0.62) | MTNR1AKDM4CKDM4E | |
| SCHEMBL11957288 | 0.73 | MTNR1A (0.52) | MTNR1AKDM4CHTR2AHTR2CFAAH | |
| SCHEMBL6649870 | 0.72 | MTNR1A (0.71) | MTNR1AMAPK1KDM4E | |
| SCHEMBL7771835 | 0.72 | KDM4C (0.46) | MTNR1AKDM4CHTR2AHTR2CFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389638-A | Nervous system disorders | ABBOTT LABORATORIES (US) | 1995-02-14 | — | — | US | disclosed |