Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011204 | 0.78 | MTNR1A (0.82) | MTNR1AKDM4C | |
| SCHEMBL31688731 | 0.76 | MTNR1A (0.47) | MTNR1AKDM4CFAAHMEN1ALDH1A1 | |
| SCHEMBL9251696 | 0.76 | MTNR1A (0.51) | MTNR1AKDM4CFAAHHTR2AHTR2C | |
| SCHEMBL29714981 | 0.75 | POLB (0.45) | MTNR1AKDM4CFAAHHTR2AALDH1A1 | |
| SCHEMBL166877 | 0.74 | KDM4C (0.51) | MTNR1AKDM4CFAAHMEN1ALDH1A1 | |
| SCHEMBL11754720 | 0.74 | KDM4C (0.46) | MTNR1AKDM4CFAAHMEN1ALDH1A1 | |
| SCHEMBL9160629 | 0.73 | MTNR1A (0.48) | MTNR1AKDM4CFAAHMEN1ALDH1A1 | |
| SCHEMBL7377233 | 0.73 | KDM4C (0.47) | MTNR1AKDM4CFAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL7141884 | 0.73 | KDM4E (0.47) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9362028 | 0.73 | SIGMAR1 (0.56) | MEN1ALDH1A1MAPTPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389638-A | Nervous system disorders | ABBOTT LABORATORIES (US) | 1995-02-14 | — | — | US | disclosed |