Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 5/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262507 | 0.98 | KMT2A (0.48) | KMT2AATMMGLLNAMPTL3MBTL1 | |
| SCHEMBL9256514 | 0.93 | KMT2A (0.48) | KMT2AATMMGLLNAMPTCYP3A4 | |
| SCHEMBL9263304 | 0.84 | MGLL (0.47) | KMT2AMGLLALDH1A1FAAH | |
| SCHEMBL9256320 | 0.81 | MGLL (0.45) | KMT2AMGLLALDH1A1MAPT | |
| SCHEMBL9264047 | 0.81 | MGLL (0.44) | KMT2AMGLLALDH1A1MAPTFAAH | |
| SCHEMBL9259528 | 0.79 | MGLL (0.45) | KMT2AMGLLALDH1A1MAPT | |
| SCHEMBL9254614 | 0.78 | MGLL (0.43) | KMT2AMGLLALDH1A1MAPTFAAH | |
| SCHEMBL9254998 | 0.78 | ALDH1A1 (0.51) | KMT2AATMMGLLL3MBTL1ALDH1A1 | |
| SCHEMBL9257887 | 0.78 | MGLL (0.41) | KMT2AMGLLALDH1A1FAAH | |
| SCHEMBL9261790 | 0.76 | MGLL (0.46) | KMT2AMGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |