Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251828 | 1.00 | ALOX5 (0.41) | ALOX5PPARATAS1R3TAS1R1PPARG | |
| SCHEMBL6042289 | 0.78 | SIGMAR1 (0.42) | PPARAPPARGLMNA | |
| SCHEMBL6042296 | 0.78 | SIGMAR1 (0.42) | PPARAPPARGLMNA | |
| SCHEMBL15573651 | 0.72 | ALOX5 (0.49) | ALOX5PPARATAS1R3TAS1R1PPARG | |
| SCHEMBL31634313 | 0.72 | ALOX5 (0.49) | ALOX5PPARATAS1R3TAS1R1PPARG | |
| SCHEMBL9045547 | 0.72 | PTGS2 (0.44) | ALDH1A1 | |
| SCHEMBL14833024 | 0.72 | PTGS2 (0.44) | ALDH1A1 | |
| SCHEMBL9097143 | 0.70 | ALOX5 (0.44) | ALOX5PPARATAS1R3TAS1R1PPARG | |
| SCHEMBL20236040 | 0.70 | USP2 (0.57) | KDM4EALDH1A1USP2LMNAMMP9 | |
| SCHEMBL31681954 | 0.70 | USP2 (0.57) | KDM4EALDH1A1USP2LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |