Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 8/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256124 | 0.91 | HTT (0.35) | ITGB3ITGA2BPLAUF2MEN1 | |
| SCHEMBL9251855 | 0.85 | PPARD (0.46) | ITGB3ITGA2BMPOPPARDPPARA | |
| SCHEMBL9254301 | 0.84 | ITGB3 (0.42) | ITGB3ITGA2BMPOPPARDPLAU | |
| SCHEMBL9254081 | 0.82 | F10 (0.41) | ITGB3ITGA2BMPOPPARDPLAU | |
| SCHEMBL9254458 | 0.79 | ITGB3 (0.52) | ITGB3ITGA2BPLAUPLGMEN1 | |
| SCHEMBL9251983 | 0.76 | HTT (0.43) | ITGB3ITGA2BPPARDPLAUPPARA | |
| SCHEMBL9257540 | 0.75 | PLAU (0.39) | ITGB3ITGA2BPLAUPLGMEN1 | |
| SCHEMBL9251306 | 0.73 | HTT (0.37) | ITGB3ITGA2BPLAUF2MEN1 | |
| SCHEMBL9254020 | 0.73 | NQO2 (0.36) | ITGB3ITGA2BPLAUNQO2F2 | |
| SCHEMBL9255039 | 0.72 | S1PR1 (0.43) | ITGB3ITGA2BPLAUMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |