Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250408 | 0.91 | CHEK1 (0.38) | S1PR1ITGB3ITGA2BMAPTL3MBTL1 | |
| SCHEMBL9255778 | 0.86 | ITGB3 (0.37) | ITGB3ITGA2BF10 | |
| SCHEMBL9254490 | 0.86 | F10 (0.38) | ITGB3ITGA2BPOLBF10 | |
| SCHEMBL9258892 | 0.83 | ITGB3 (0.39) | ITGB3ITGA2BMAPTMEN1KMT2A | |
| SCHEMBL9254911 | 0.82 | F7 (0.37) | ITGB3ITGA2BPLAUF10 | |
| SCHEMBL9253735 | 0.81 | F10 (0.38) | ITGB3ITGA2BF10 | |
| SCHEMBL9251429 | 0.80 | TMPRSS15 (0.36) | ITGB3ITGA2BF10 | |
| SCHEMBL9253817 | 0.80 | TMPRSS15 (0.38) | ITGB3ITGA2BF10 | |
| SCHEMBL9256974 | 0.80 | ITGB3 (0.51) | ITGB3ITGA2BFFAR1F10 | |
| SCHEMBL9253132 | 0.80 | ITGB3 (0.51) | ITGB3ITGA2BFFAR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |